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PPEP-002
2 CDC25C, CHK1 and CHK2 Substrate, phosphorylated
Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-pSer-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg-NH2
Size:1mg
P1(RMB):701
MW:2780.2
One letter sequence:KKKVSRSGLYR-pS-PSMPENLNRPR-NH2
Molecular Formula:
Description:This amino acids 206 to 225 fragment corresponds to the phosphatase CDC25C, phosphorylated at position Ser217. This peptide can be used for checkpoint kinases CHK1 and CHK2 assays.
Literature Reference:Jiang, X. et al. Mol. Canc. Ther. 3: 1221 (2004) O’Neill, T. et al. J. Biol. Chem. 277, 16102 (2002 Davies, S. et al. Biochem. J. 351, 95 (2000) Oh, H. et al. Proc. Natl. Acad. Sci. USA 100, 5378 (2003).
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