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LHRH-016A
Deslorelin High acetate salt
Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt High acetate salt
Size:5mg
P1(RMB):236
MW:1282.47
One letter sequence:Pyr-HWSYwLRP-NHEt
Molecular Formula:C64H83N17O12
Description:Short-term administration of deslorelin stimulates the formation of LH and FSH, which induce an increase in the production of testosterone and estradiol. Prolonged administration of the GnRH agonist causes a sustained down-regulation of circulating LH and FSH levels and hence suppression of steroidogenesis.
Literature Reference:D.H.Coy et al., J. Med. Chem., 19, 423 (1976) K.Sundaram et al., Life Sci., 28, 83 (1981) B.Candas et al., J. Clin. Endocrinol. Metab., 70, 1046 (1990) P.P.Feuillan et al., J. Endocrinol. Invest., 24, 734 (2001) Merck Index, 14th ed., No. 2923, (2006)
Cas:57773-65-6
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