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IMMO-003B
Thymic Factor,Serum Thymic Factor, STF, Thymulin
Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn Trifluoroacetate salt
Size:25mg
P1(RMB):2030
MW:858.86
One letter sequence:Pyr-AKSQGGSN
Molecular Formula:C33H54N12O15
Description:For exerting its anti-inflammatory and immunomodulatory activity, the peptide hormone thymulin, pEAKSQGGSN, requires the presence of Zn(II). Thymulin showed promising results in experimental models of lung diseases as well as potential as an analgesic peptide.
Literature Reference:J.F.Bach et al., Bull. Inst. Pasteur, 325 (1978) T.L.K.Low and A.L.Goldstein, Springer Semin. Immunopathol., 2, 169 (1979) J.J.E.Haddad et al., Biochem. Biophys. Res. Commun., 274, 500 (2000) S.C.Land and F.Darakshan, Am. J. Physiol. Lung Cell. Mol. Physiol., 286, L473 (2004) M.Dardenne et al., Ann. N. Y. Acad. Sci., 1088, 153 (2006) T.Henriques-Coelho et al., Endocrinology, 149, 4367 (2008) P.C.Reggiani et al., Ann. N. Y. Acad. Sci., 1153, 98 (2009) H.Folch et al., Biol. Res., 43, 291 (2010) M.Santos et al., Expert Opin. Ther. Targets, 14, 131 (2010)
Cas:63958-90-7
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