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FBP-001A
Fibrinogen-Binding Peptide
Glu-His-Ile-Pro-Ala
Size:5mg
P1(RMB):176
MW:565.63
One letter sequence:EHIPA
Molecular Formula:C25H39N7O8
Description:Fibrinogen is a cofactor in platelet activation. This peptide binds to fibrinogen and inhibits the adhesion of platelets to fibrinogen, platelet aggregation and the adhesion of platelets to vitronectin. The peptide has the characteristics expected of a mimic of a glycoprotein IIb/IIIa ligand binding site.
Literature Reference:T.K.Gartner and D.B.Taylor, Proc. Soc. Exp. Biol. Med., 198, 649 (1991)
Cas:137235-80-4
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