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PKCP-012A
CKS-17
Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu
Size:1.0mg
P1(RMB):398
MW:1942.3
One letter sequence:LQNRRGLDLLFLKEGGL
Molecular Formula:C87H148N26O24
Description:Peptide isolated from a highly conserved region of the immunosuppressive retroviral envelope protein p15E that is also capable of inhibiting lymphocyte proliferation, B cell activation, natural killer cell cytotoxicity, and monocyte-mediated tumor cytotoxicity. It has been found that CKS-17 leads to the rise of intracellular cAMP levels that may affect on several physiological cellular funtions.
Literature Reference:R. A. J. Oostendorp et al., Eur. J. Immunol., 22, 1505 (1992)
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