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CASP-008A
Ac-YVAD-2,6-dimethylbenzoyloxymethylketone
Ac-Tyr-Val-Ala-Asp-2,6- dimethylbenzoyloxymethylketone
Size:1.0mg
P1(RMB):306
MW:654.72
One letter sequence:Ac-YVAD-2,6- diMhylbenzoyloxyMhylketone
Molecular Formula:C33H42N4O10
Description:Highly selective, competitive and irreversible inhibitor of caspase-1 (ICE). Inactivation of the enzyme occurs with a rate limited by diffusion and is relatively inert toward other bionucleophiles such as glutathione, thus making it an excellent candidate for in vivo studies of enzyme inhibitors.
Literature Reference:N.A. Thornberry et al., Biochemistry, 33, 3934 (1994)
Cas:[154674-81-4]
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