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CASP-003A
Ac-Trp-Glu-His-Asp-AMC
Ac-Trp-Glu-His-Asp-AMC
Size:1mg
P1(RMB):91.95
MW:784.8
One letter sequence:Ac-WEHD-AMC
Molecular Formula:C38H40N8O11
Description:With a Kcat/Km of 3.3•106M-1s-1 this fluorogenic caspase-1 substrate is cleaved 50-fold more efficiently than CASP-010. This phenomena shows that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
Literature Reference:T.A. Rano et al., Chem. Biol. 4, 149 (1997)
Cas:[189275-74-9]
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